Endocrine Abstracts

Objective: To evaluate the effects of metformine newly using in clinical practice to ameliorate insulin resistance on paraoxonase activity and oxidative stress in obese insulin resistant women.Materials and methods: Sixty-seven obese (BMI≥30 kg/m2) women were enrolled into this study. Serum fasting (F.Glc) and postprandial glucose (P.Glc), insulin, uric acid (UA), paraoxonase (PON1), Arylesterase (AET), malondialdehyde (MDA), cupper-MDA ...